Table 3.

CO transfer (Tlco) subcomponents during submaximal exercise (group A, 20 heart failure patients and 20 normal controls)

	Heart failure subjects		Normal controls
	Rest	5th minute	Rest	5th minute
Dm (ml/min/mm Hg)	29.1 (8.4)*	36.4 (12.8)*†	46.9 (14.0)	51.3 (19.2)†
Dm/Va	5.4 (1.3)*	6.6 (2.5)*†	8.0 (2.1)	8.7 (2.5)†
Vc (ml)	109 (42)	145 (65)*†	104 (39)	134 (31)†

Data are presented as mean (SD).

*p < 0.01 v normal controls; †p < 0.01 v values at rest.

Dm, molecular diffusion for carbon monoxide across the alveolar–capillary membrane; Dm/Va, Dm normalised for alveolar volume; Vc, pulmonary capillary blood volume.