Table 2.
Results of the partitioned proportional hazards model analysis for seven five year periods with coronary heart disease deaths as end point and six risk factors as covariates
Follow up period | Deaths/ sample | Factor | Coefficient | T Value | Delta for computing hazard ratios | Hazards ratios | 95 % CI |
Years 1–5 | 9/1622 | Age | 0.0229 | 0.32 | 5 years | 1.12 | 0.56 to 2.26 |
Systolic blood pressure | 0.0096 | 0.63 | 20 mm Hg | 1.21 | 0.67 to 2.20 | ||
Cholesterol | 0.8507 | 3.47 | 1 mmol/l | 2.34 | 1.45 to 3.79 | ||
Physical activity | –0.1081 | –0.23 | 1 score unit | 0.90 | 0.36 to 2.25 | ||
Body mass index | –0.0274 | –0.30 | 1 unit | 0.97 | 0.81 to 1.16 | ||
Cigarettes | 0.0168 | 0.54 | 10 cigarettes | 1.18 | 0.64 to 2.18 | ||
Years 6–10 | 16/1542 | Age | 0.1012 | 1.87 | 5 years | 1.66 | 0.98 to 2.82 |
Systolic blood pressure | 0.0367 | 4.12 | 20 mm Hg | 2.08 | 1.47 to 2.95 | ||
Cholesterol | 0.2630 | 1.15 | 1 mmol/l | 1.30 | 0.83 to 2.04 | ||
Physical activity | –0.8927 | –2.89 | 1 score unit | 0.41 | 0.22 to 0.75 | ||
Body mass index | –0.1085 | –1.49 | 1 unit | 0.90 | 0.78 to 1.03 | ||
Cigarettes | –0.0126 | –0.43 | 10 cigarettes | 0.88 | 0.50 to 1.57 | ||
Systolic blood pressure* | 0.0411 | 4.02 | 20 mm Hg | 2.27 | 1.53 to 3.39 | ||
Cholesterol* | 0.4950 | 2.00 | 1 mmol/l | 1.64 | 1.01 to 2.06 | ||
Years 11–15 | 28/1428 | Age | 0.1208 | 3.01 | 5 years | 1.83 | 1.23 to 2.71 |
Systolic blood pressure | 0.0195 | 2.19 | 20 mm Hg | 1.48 | 1.04 to 2.09 | ||
Cholesterol | 0.0193 | 0.11 | 1 mmol/l | 1.02 | 0.72 to 1.44 | ||
Physical activity | –0.1201 | –0.42 | 1 score unit | 0.89 | 0.51 to 1.55 | ||
Body mass index | 0.0173 | 0.33 | 1 unit | 1.02 | 0.92 to 1.13 | ||
Cigarettes | 0.0669 | 3.75 | 10 cigarettes | 1.95 | 1.38 to 2.77 | ||
Systolic blood pressure* | 0.0275 | 2.76 | 20 mm Hg | 1.53 | 1.18 to 2.56 | ||
Cholesterol* | 0.0193 | 0.10 | 1 mmol/l | 1.02 | 0.69 to 1.50 | ||
Years 16–20 | 33/1258 | Age | 0.0373 | 1.03 | 5 years | 1.20 | 0.84 to 1.72 |
Systolic blood pressure | 0.0305 | 3.84 | 20 mm Hg | 1.84 | 1.35 to 2.51 | ||
Cholesterol | 0.3171 | 2.01 | 1 mmol/l | 1.37 | 1.01 to 1.87 | ||
Physical activity | –0.2389 | –0.96 | 1 score unit | 0.78 | 0.48 to 1.28 | ||
Body mass index | –0.0047 | –0.09 | 1 unit | 1.00 | 0.90 to 1.10 | ||
Cigarettes | –0.0072 | –0.36 | 10 cigarettes | 0.93 | 0.63 to 1.38 | ||
Years 21–25 | 35/1063 | Age | 0.0657 | 1.88 | 5 years | 1.39 | 0.99 to 1.96 |
Systolic blood pressure | 0.0045 | 0.47 | 20 mm Hg | 1.09 | 0.75 to 1.59 | ||
Cholesterol | 0.1315 | 0.82 | 1 mmol/l | 1.14 | 0.83 to 1.56 | ||
Physical activity | –0.2272 | –0.94 | 1 score unit, | 0.80 | 0.50 to 1.28 | ||
Body mass index | 0.0785 | 1.62 | 1 unit | 1.08 | 0.98 to 1.19 | ||
Cigarettes | 0.0300 | 1.86 | 10 cigarettes | 1.35 | 0.98 to 1.85 | ||
Years 26–30 | 42/864 | Age | 0.0648 | 1.96 | 5 years | 1.38 | 1.00 to 1.91 |
Systolic blood pressure | 0.0290 | 2.19 | 20 mm Hg | 1.79 | 1.06 to 3.00 | ||
Cholesterol | 0.0075 | 2.09 | 1 mmol/l | 1.01 | 1.00 to 1.01 | ||
Physical activity | –0.6464 | –3.17 | 1 score unit | 0.52 | 0.35 to 0.78 | ||
Body mass index | –0.0069 | –0.15 | 1 unit | 0.99 | 0.91 to 1.09 | ||
Cigarettes | 0.0302 | 2.06 | 10 cigarettes | 1.35 | 1.01 to 1.80 | ||
Years 31–35 | 51/653 | Age | 0.1712 | 5.40 | 5 years | 2.35 | 1.72 to 3.21 |
Systolic blood pressure | 0.0058 | 0.63 | 20 mm Hg | 1.12 | 0.78 to 1.61 | ||
Cholesterol | 0.2591 | 1.97 | 1 mmol/l | 1.30 | 1.00 to 1.68 | ||
Physical activity | –0.0869 | –0.36 | 1 score unit | 0.92 | 0.57 to 1.47 | ||
Body mass index | –0.0054 | –0.11 | 1 unit | 0.99 | 0.90 to 1.10 | ||
Cigarettes | 0.0061 | 0.39 | 10 cigarettes | 1.06 | 0.78 to 1.44 |
*Derived from independent models with estimates adjusted for specific risk factor changes.