Figure 5.
Effect of graded concentrations of GABA on the conversion of [3H]pregnenolone into 17-hydroxypregnenolone and dihydrotestosterone (17OH-Δ5P/5α-DHT; A), dehydroepiandrosterone (DHEA; B), 17-hydroxyprogesterone (17OH-P; C) and progesterone (P; D) by hypothalamic slices. The values were obtained from experiments similar to those presented in Fig. 4. Results are expressed as percentages of the amount of each steroid formed in the absence of GABA. Values are the mean (±SEM) of four independent experiments.