Table 2.
Clinical and echocardiographic characteristics of women in whom prepregnancy echocardiographic data were available and in whom hypertrophic cardiomyopathy was diagnosed before pregnancy and data were collected within one year of pregnancy
| Number of patients | 40 (31.5%) |
| Mean age at first pregnancy | 24 (3.1) (17–38) |
| Angina | 10 (25%) |
| Dyspnoea (NYHA ⩾II) | 6 (15%) |
| Syncope | 3 (7.5%) |
| Palpitations | 7 (17.5%) |
| Ventricular tachycardia | 0 (0%) |
| Non-sustained ventricular tachycardia | 4 (10%) |
| Paroxysmal atrial fibrillation | 2 (5%) |
| Sustained atrial fibrillation | 0 (0%) |
| FHSCD | 8 (20%) |
| ABPR | 7 (17.5%) |
| Mean %Vo2 max | 74 (12) (61–105) |
| Mean MLVWT (mm) | 23 (3.7) (14–31) |
| Mean LVED (mm) | 43 (3.1) (31–57) |
| Mean LVES (mm) | 27 (6.0) (15–40) |
| Mean fractional shortening (%) | 38 (9.0) (29–50) |
| Mean LVOTG (mmHg) | 14 (4.8) (1–41) |
| Mean left atrium (mm) | 41 (2.5) (29–54) |
| Implantable cardioverter-defibrillator | 1 (2.5%) |
| Myectomy | 2 (5%) |
| Pacemaker | 2 (5%) |
Data are presented as mean (SD) and range.
%Vo2 max, maximal oxygen consumption during upright exercise testing; ABPR, abnormal blood pressure response to exercise; FHSCD, family history of sudden cardiac death; LVED, left ventricular end diastolic diameter; LVES, left ventricular end systolic diameter; LVOTG, left ventricular outflow tract gradient; MLVWT, maximal left ventricular wall thickness; NYHA, New York Heart Association.