Table 3.
Normal control (n=493) | IHD control (n=427) | MI survivor (n=828) | Normal control v IHD control OR (95% CI) | Normal control v MI survivor OR (95% CI) | |
Wild type | 268 (54.4%) | 249 (58.3%) | 468 (56.5%) | 1.17 (0.90 to 1.5) | 1.14 (0.87 to 1.5) |
H63D homozygote | 10 (2.0%) | 9 (2.1%) | 23 (2.8%) | 1.02 (0.41 to 2.6) | 1.22 (0.51 to 2.9) |
H63D heterozygote | 115 (23.3%) | 98 (23.0%) | 198 (23.9%) | 0.97 (0.71 to 1.3) | 1.04 (0.76 to 1.4) |
Compound heterozygote | 15 (3.0%) | 7 (1.6%) | 31 (3.7%) | 0.53 (0.21 to 1.3) | 0.87 (0.42 to 1.8) |
C282Y homozygote | 5 (1.0%) | 3 (0.7%) | 7 (0.8%) | 0.71 (0.17 to 3.0) | 1.20 (0.23 to 6.2) |
C282Y heterozygote | 80 (16.2%) | 61 (14.3%) | 101 (12.2%) | 0.88 (0.61 to 1.3) | 0.70 (0.48 to 1.04) |
None of the genotype groups achieved significance.
HFE, haemochromatosis gene.