Table 1.

Clinical details of the patients

	Standard AVR	Silzone AVR	p Value	Standard MVR/DVR	Silzone MVR/DVR	p Value
Number of patients	70	32		35/11	13/6
Follow up (years)	326	104		203	49
Age (years)
Mean (SD)	64 (10)	61 (10)	0.137	66 (7)	61 (10)	0.041
Range	36 to 80	41 to 78		47 to 81	44 to 76
Sex
Male	43 (61)	20 (63)	0.918	16 (35)	1 (5)	0.014
Female	27 (39)	12 (37)	0.918	30 (65)	18 (95)	0.014
Current smoking	11 (16)	6 (19)	0.703	3 (7)	3 (16)	0.240
NYHA class
I–II	39 (56)	12 (37)	0.088	9 (20)	2 (10)	0.377
III–IV	31 (44)	20 (63)	0.088	37 (80)	17 (90)	0.377
CABG at operation	21 (30)	8 (25)	0.603	15 (33)	1 (5)	0.020
Angina pectoris	36 (51)	17 (53)	0.874	12 (26)	1 (5)	0.056
CAD at angiography	30 (43)	10 (31)	0.265	21 (46)	3 (16)	0.023
Previous thromboembolism	6 (9)	4 (13)	0.536	11 (24)	3 (16)	0.469
Concomitant disease
Systemic hypertension	18 (26)	10 (31)	0.561	11 (24)	2 (11)	0.220
Pulmonary hypertension	37 (53)	14 (44)	0.393	36 (78)	19 (100)	0.027
Diabetes mellitus	7 (10)	2 (6)	0.536	5 (11)	1 (5)	0.478
Previous myocardial infarct	5 (7)	1 (3)	0.424	4 (9)	0 (0)	0.185
Congestive heart failure	11 (16)	2 (6)	0.184	31 (67)	6 (32)	0.008
Atrial fibrillation/flutter	8 (11)	4 (13)	0.876	37 (80)	16 (84)	0.721
Previous valvotomy	2 (3)	0 (0)	0.627	5 (11)	7 (37)	0.040
Valve pathology
Rheumatic	17 (24)	5 (16)	0.324	39 (85)	18 (95)	0.267
Congenital	29 (41)	19 (59)	0.092	0 (0)	0 (0)	1.000
Degenerative	10 (14)	2 (6)	0.242	0 (0)	0 (0)	1.000
Senile calcification	11 (16)	6 (19)	0.703	0 (0)	0 (0)	1.000
Valve lesion
Stenosis or mixed lesion	64 (91)	29 (91)	0.894	33 (72)	17 (90)	0.123
Pure regurgitation	6 (9)	3 (9)	0.894	13 (28)	2 (10)	0.123

Values are n (%) unless stated otherwise.

AVR, aortic valve replacement; CABG, coronary artery bypass graft; CAD, coronary artery disease; DVR, double valve replacement; MVR, mitral valve replacement; NYHA, New York Heart Association.