Skip to main content
. 2003 Nov;89(11):1327–1334. doi: 10.1136/heart.89.11.1327

Table 2.

Clinical characteristics of the studies included in the meta-analysis

Reference Mean age (years) Male (%) CAD (%) DM (%) Isotope used Test used Positivity criterion Preop revascularisation (%) Op cancelled (%) TP FN TN FP
Ambulatory electrocardiography
Ouyang5 64 71 71 29 NA Preop monitoring ST depression >1 mm 0 0 2 0 9 13
Raby6 66 70 40 21 NA Preop monitoring ST depression >1 mm 0 0 3 1 143 29
Pasternack7 70 79 41 – NA Preop monitoring ST depression >1 mm 0 0 9 0 73 118
Mangano8 69 100 51 25 NA Preop monitoring ST depression >1 mm/ST elevation >2 mm 0 0 1 5 109 25
Fleischer9 66 61 57 34 NA Preop monitoring ST depression >1 mm/ST elevation >2 mm 0 0 1 2 49 15
McPhail10 67 86 – – NA Preop monitoring ST depression >1 mm 0 0 5 4 62 29
Kirwin11 73 55 66 47 NA Preop monitoring ST depression >1 mm 0 0 1 14 73 8
Fleischer12 69 50 72 43 NA Preop monitoring ST depression >1 mm/ST elevation >2 mm 0 0 2 2 64 18
Exerciseelectrocardiography
Cutler13 62 77 – – NA Treadmill/arm ergometry ST depression >1 mm 8 0 8 1 79 32
Gardine14 – – – – NA Treadmill ST depression >1 mm 0 0 1 0 10 6
von Knorring15 – – 52 – NA Treadmill ST depression >1 mm 0 0 2 1 78 24
Hanson16 62 73 20 – NA Arm ergometry ST depression >1 mm 0 0 1 0 32 41
Leppo17 67 62 51 18 NA Treadmill/arm ergometry ST depression >1.5 mm 0 0 3 4 44 9
Kaaja18 – 67 29 22 NA Bicycle ST depression >1 mm 0 0 2 0 44 2
Urbinati19 62 74 15 46 NA Bicycle ST depression >1 mm 0 0 2 0 93 48
Radionuclide ventriculography
Fiser20 61 100 25 – Tc99m NA EF <30% 0 0 2 0 18 0
Pasternack21 70 96 34 – Tc99m NA EF <35% 0 0 4 4 41 1
Mosley22 – 90 63 – Tc99m NA EF <35% 0 0 3 1 36 1
Pasternack23 66 80 36 – Tc99m NA EF <35% 1 0 6 8 84 1
Kazmers24 68 – 42 7 Tc99m NA EF <35% 0 0 1 4 46 9
Franco25 68 55 61 – Tc99m NA EF <35% 0 0 3 12 58 12
McCann26 68 87 49 – Tc99m NA EF <35% 0 0 1 2 83 18
Fletcher27 68 79 50 – Tc99m NA EF <35% 0 0 3 0 62 7
Myocardial perfusion scintigraphy
Boucher28 63 96 100 – T201 Planar Fixed or reversible perfusion defect 11 0 3 0 20 25
Cutler29 65 69 34 – T201 Planar Fixed or reversible perfusion defect 5 8 9 0 62 30
Fletcher30 64 72 27 – T201 Planar Fixed or reversible perfusion defect 7 0 2 0 57 3
Sachs31 60 83 30 – T201 Planar Reversible perfusion defect 0 0 2 0 32 12
Lane32 65 65 63 100 T201 Planar Fixed or reversible perfusion defect 0 0 9 0 20 72
Eagle33 66 71 29 18 T201 Planar Reversible perfusion defect 0 0 13 2 116 69
Younis34 65 72 42 31 T201 Planar Fixed or reversible perfusion defect 4 15 8 0 51 48
McEnroe35 69 58 28 – T201 Planar Fixed or reversible perfusion defect 8 0 4 2 44 37
Strawn36 66 – 62 15 T201 Planar Reversible perfusion defect 13 9 1 3 18 31
Waters37 – – 100 – T201 Planar Fixed or reversible perfusion defect 4 4 3 0 11 12
Mangano38 – 98 45 25 T201 Planar/SPECT Fixed or reversible perfusion defect 0 0 2 1 19 38
Hendel39 – 65 35 23 T201 Planar Reversible perfusion defect 0 0 23 5 155 144
Madsen40 65 65 22 – T201 Planar Fixed or reversible perfusion defect 0 0 5 0 20 40
McPhail10 67 86 – – Tc99m Planar Fixed or reversible perfusion defect 0 0 6 3 67 24
Bry41 66 69 30 34 T201 Planar Fixed or reversible perfusion defect 4 0 17 0 97 114
Baron42 63 – 36 9 T201 SPECT Fixed or reversible perfusion defect 0 0 26 16 187 228
Ombrellaro43 68 62 38 23 T201/Tc99m Planar Fixed or reversible perfusion defect 7 0 2 2 125 33
Erickson45 67 88 26 15 T201 Planar Fixed or reversible perfusion defect 3 0 6 1 55 80
Vanzetto46 65 94 36 13 T201 SPECT Fixed or reversible perfusion defect 0 0 11 1 50 72
Klonaris47 67 87 36 32 T201 Planar Fixed or reversible perfusion defect 0 0 7 1 43 116
Huang48 68 89 12 27 T201 SPECT Fixed or reversible perfusion defect 0 0 5 0 24 75
de Virgilio49 65 96 26 33 T201 Planar Fixed or reversible perfusion defect 4 0 2 0 27 30
de Virgilio50 65 78 29 74 T201/Tc99m SPECT Fixed or reversible perfusion defect 0 0 3 1 35 41
Dipyridamole stress echocardiography
Tischler51 68 61 34 29 NA NA New or worsening RWMA during test 0 0 4 0 100 5
Pasquet52 67 84 19 17 NA NA New or worsening RWMA during test 9 0 2 3 99 25
Rossi53 66 80 39 76 NA NA New or worsening RWMA during test 0 0 4 3 74 22
Sicari54 66 88 20 11 NA NA New or worsening RWMA during test 0 0 15 2 419 73
Dobutamine stress echocardiography
Lalka55 64 78 30 18 NA NA New or worsening RWMA during test 0 0 8 1 21 30
Davila-Roman56 67 73 63 19 NA NA New or worsening RWMA during test 14 0 2 0 68 8
Langan57 69 84 31 10 NA NA New or worsening RWMA during test 5 6 3 0 31 40
Poldermans58 68 89 31 12 NA NA New or worsening RWMA during test 0 0 5 0 96 30
Eichelberger59 68 60 37 29 NA NA New or worsening RWMA during test 0 0 2 0 48 25
Poldermans60 67 85 31 11 NA NA New or worsening RWMA during test 0 0 17 0 228 55
Shafritz61 66 64 33 17 NA NA New or worsening RWMA during test 0 0 1 0 30 11
Boersma62 69 78 43 15 NA NA New or worsening RWMA during test 0 0 29 14 863 187

CAD, coronary artery disease; DM, diabetes mellitus; EF, ejection fraction; FN, false negative; FP, false positive; NA, not applicable; Op, operation; Preop, preoperative; RWMA, resting wall motion abnormality; TN, true negative; TP, true positive; -, missing values.