Table 2.
Concordance between the prevalence of diastolic dysfunction using different published reference ranges for individual echocardiographic measures
| Age range (years) | E:A ratio* | ||||
| Framingham study20 | Mantero et al18 | Klein et al24 | Cardiovascular health study22 | ||
| Men | Women | ||||
| 40–49 | 1/5 | 1/5 | 1/5 | NA | NA |
| 50–59 | 1/8 | 0/8 | 3/8 | NA | NA |
| 60–69 | 1/19 | 4/19 | 4/19 | 1/5† | 0/7† |
| 70–79 | NA | 2/47‡ | NA | 0/11 | 4/34 |
| ⩾70 | 2/64 | NA | 2/64§ | NA | NA |
| >80 | NA | NA | NA | 3/4 | 5/15 |
| IVRT | ||||||||
| Mantero et al18 | Klein et al24 | |||||||
| 40–49 | 4/5 | 3/5 | ||||||
| 50–59 | 5/8 | 0/8 | ||||||
| 60–69 | 4/20 | 0/20 | ||||||
| 70–79 | 20/51§ | NA | ||||||
| >70 | NA | 27/67 | ||||||
| AFF | |||||||
| Framingham study20 | Mantero et al18 | Voutilainen et al21 | |||||
| 40–49 | 3/5 | 0/5 | NA | ||||
| 50–59 | 7/8 | 0/8 | NA | ||||
| 40–60 | 10/13 | 0/13 | 5/13 | ||||
| >60 | NA | NA | 8/82 | ||||
| 60–69 | 7/19 | 1/19 | NA | ||||
| 70–79 | NA | 6/46§ | NA | ||||
| ⩾70 | 7/63 | NA | NA | ||||
| DT | |||||
| Mantero et al18 | Klein et al24 | ||||
| *Bryg et al23 1/5 30–49 years, 1/22 51–68 years; †65–69; ‡>70; §70–80. | |||||
| A, peak atrial filling; AFF, atrial filling fraction; DT, deceleration time; E, peak rapid filling; IVRT, isovolumetric relaxation time; NA, not available. | |||||
| 40–49 | 1/5 | 1/5 | |||
| 50–59 | 0/8 | 1/8 | |||
| 60–69 | 6/20 | 2/20 | |||
| 70–79 | 9/48§ | NA | |||
| >70 | NA | 8/65 | |||