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Effect of (A) abciximab, (B) eptifibatide, and (C) tirofiban in combination with UFH or LMWH on thrombin induced P selectin expression. Platelets were prepared as described for aggregation. Platelet activation was halted at 180 or 300 seconds by the addition of paraformaldehyde before staining with anti-P selectin (CD62P) and flow cytometric analysis. Results are depicted as the mean (SEM) relative fluorescent intensity (RFI) from eight experiments.
