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. 2004 Aug;90(8):921–926. doi: 10.1136/hrt.2003.015065

Table 2.

 Abnormal cardiac scans showing asymmetry between right and left sided structures

Patient Indication GA (weeks+days) Cardiac findings Other ultrasound findings Karyotype Outcome
1 Increased NT 13+0 Asymmetry RV/LV Increased NT of 7 mm, no other findings Normal Planned for serial scans; TOP at 13 weeks, postmortem severely narrowed aortic isthmus (<300 μm).
2. Family history congenital heart disease (×2) 13+1 Asymmetry RV/LV and Ao/PA, right sided heart Diaphragmatic hernia suspected at 15 weeks; severe diaphragmatic hernia, left heart hypoplasia at 19 weeks Normal TOP at 21+3 weeks, postmortem large diaphragmatic hernia with severe lung hypoplasia, hypoplasia of the LV and severely hypoplastic aortic arch
3 Increased NT, unbalanced translocation 16+0 Asymmetry RV/LV Progressive left ventricular outflow obstruction on subsequent scans Unbalanced translocation (7/15) TOP at 23+6 weeks, postmortem severe hypoplasia of LV and aortic arch
4 Increased NT 14+1 Asymmetry RV/LV, right sided heart Limb abnormality, suspected diaphragmatic hernia Normal TOP at 14+2 weeks, no postmortem examination
5 Increased NT 13+1 Small aortic isthmus Increased NT of 7.9 mm; no other findings Normal Planned for serial scans; TOP at 13 weeks, no postmortem examination
6 Increased NT 13+3 Asymmetry RV/LV, distal aortic arch not seen Cystic hygroma 45 XO TOP at 14+0 weeks, postmortem severely narrowed aortic arch and isthmus
7 Exomphalos 14+2 Asymmetry RV/LV and Ao/PA Exomphalos Normal Live birth, successful repair of coarctation and exomphalos

LV, left ventricle.