Table 3.
Type | First choice | If refractory |
Hypercholesterolaemia | Statin | Add cholesterol absorption inhibitor, bile acid sequestrant, or nicotinic acid |
Hypertriglyceridaemia | Fibrate | Add nicotinic acid or ω3 fatty acids |
Mixed hyperlipidaemia | Statin | Substitute or add fibrate (not gemfibrozil + statin) |
Low HDL cholesterol | Statin | Substitute or add fibrate or nicotinic acid |
Check liver function before and after one month on statin.
Check renal function before and after one month on fibrate.
Check serum creatine kinase (CK) only if myalgia occurs during statin or fibrate treatment.