Table 2.
Peak exercise data during placebo and pyridostigmine administration (n = 15)
| Variable | Placebo | Pyridostigmine | p Value |
| Time to exhaustion (min, s)) | 9′18″ (18″) | 10′06″ (18″) | 0.002 |
| V̇o2 peak (ml/kg/min) | 23.6 (2.0) | 24.8 (2.0) | 0.011 |
| V̇co2 (ml/kg/min) | 20.6 (2.2) | 22.1 (2.2) | 0.031 |
| V̇e (l/min) | 57.4 (6.0) | 61.9 (6.3) | 0.024 |
| Oxygen pulse (ml/beat) | 12.9 (1) | 13.6 (1) | 0.017 |
| Heart rate (beats/min) | 129 (5) | 129 (5) | 0.313 |
| Systolic BP (mm Hg) | 192 (9) | 194 (9) | 0.349 |
| Diastolic BP (mm Hg) | 97 (4) | 92 (5) | 0.159 |
Data are mean (SE).
BP, blood pressure; V̇co2, carbon dioxide production; V̇e, minute ventilation; V̇o2, oxygen consumption.