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Phenylephrine bolus technique for measuring baroreflex sensitivity (BRS). After a bolus injection of phenylephrine there is a progressive increase in blood pressure and a reflex slowing of heart rate. BRS is calculated as the slope of the relation between systolic blood pressure and the subsequent RR interval during this ramp increase in blood pressure. Reproduced with permission from Persson PB, et al. J Hypertens 2001;19:1699–705.
