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. 2005 Jan;91(1):23–26. doi: 10.1136/hrt.2004.035014

Table 2.

 Six month outcomes in patients stratified by CYP3A4 metabolised statin use

Outcome All patients with acute coronary syndromes
No clopidogrel + no statin (n = 331) Clopidogrel + no statin (n = 180) Clopidogrel + CYP3A4 (n = 561) Clopidogrel + non-CYP3A4 (n = 91) p Value*
Death 57 (17.2%) 18 (10%) 32 (5.7%) 3 (3.3%) 0.24
MI 14 (8.3%) 10 (8.9%) 28 (7.6%) 9 (9.7%) 0.39
Stroke 3 (1.1%) 2 (1.3%) 5 (1.4%) 0 (0%) 0.70
MACE 73 (22.1%) 30 (16.7%) 64 (11.4%) 12 (13.2%) 0.54

*Comparisons between patients who received CYP3A4 statin versus a non-CYP3A4 statin with clopidogrel.

MACE, major adverse cardiac outcomes (composite of death, MI, and stroke).