Table 1.
Association between echocardiographically determined LVH and IGF-I genotypes
| IGF-I genotype | Cases* (n = 358) | Controls (n = 1320) | OR model 1† | OR model 2‡ |
| Homozygous 192 base pair allele | 145 (41%) | 587 (44%) | 1.00 (reference) | 1.00 (reference) |
| Heterozygous 192 base pair allele | 166 (46%) | 600 (46%) | 1.13 (0.88 to 1.46) | 1.11 (0.86 to 1.43) |
| Non-carrier 192 base pair allele | 47 (13%) | 133 (10%) | 1.50 (1.02 to 2.21) | 1.49 (1.01 to 2.20) |
*LVH was considered present when left ventricular mass index was ⩾104 g/m2 in women and 116 g/m2 in men.
†Adjusted for age and sex, allele effect relation p trend <0.05
‡Adjusted for age, sex, BMI, hypertension, and diabetes mellitus
Data are presented as percentages of cases or controls and as odds ratios (OR) with 95% confidence interval.