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. 2005 Feb;91(2):207–212. doi: 10.1136/hrt.2003.032011

Table 1.

 Characteristics of adult patients undergoing surgery for congenital heart disease over three time periods

All eras Era 1 (1/1/90–30/4/94) Era 2 (1/5/94–31/8/98) Era 3 (1/8/98–31/12/02) p Value*
Number of procedures 474 165 159 149
Number of patients 438 151 148 139
Women 212 (44.7%) 84 (50.9%) 60 (37.7%) 68 (45.6%) 0.0567†
Men 262 (55.3%) 81 (49.1%) 99 (62.3%) 81 (54.4%)
Age (years) 25.4 (18.7) 25.4 (20.7) 27.0 (18.7) 23.9 (17.3) 0.0437‡
Repeat procedures 162 (34.2%) 41 (24.8%) 47 (29.6%) 74 (49.7%) <0.0001†§
NYHA class
    I 2 (0.7%) 2 (2.6%) 0 (0.0%) 0 (0.0%) 0.0456†¶
    II 92 (33.3%) 35 (44.9%) 31 (31.6%) 26 (26.3%)
    III 124 (44.9%) 28 (35.9%) 46 (46.9%) 50 (50.5%)
    IV 58 (21.0%) 13 (16.7%) 21 (21.4%) 23 (23.2%)

Data are median (interquartile range) or number (%).

*For differences across the three time eras; †χ2 test; ‡Kruskal-Wallis rank test; §era 3 v era 1 and era 3 v era 1, p<0.001; ¶more patients were in New York Heart Association (NYHA) class I and II and fewer in NYHA class III and IV in era 1 than in eras 2 and 3 (appendix 2).