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. 2005 Mar;91(3):354–361. doi: 10.1136/hrt.2003.030601

Table 3.

 Multivariate analysis of haemodynamic variables that independently determine transvalvar pressure gradients

Variable Transvalvar pressure gradient
Peak to peak Peak Mean
Predicted gradient*
    p Value <0.001 <0.001 <0.001
    ΔR2 0.67 0.89 0.89
Systolic arterial pressure NS NS NS
Diastolic arterial pressure NS NS NS
Pulse pressure NS NS NS
Systemic arterial resistance NS NS NS
Systemic arterial compliance
    p Value <0.001 NS NS
    ΔR2 0.20 NA NA
Multivariate model
    p Value <0.001 <0.001 <0.001
    ΔR2 0.87 0.89 0.89

p Value and ΔR2 value for each independent variable in the multivariate predictive model are given. ΔR2 represents the respective contribution of the variable to the variance of TPG.

*Pressure gradient predicted by equation 8 from the energy loss coefficient and the mean systolic flow rate measured by Doppler echocardiography.

NA, not applicable; NS, not significant.