Table 1.
Factor (level or increment) | Men (n = 966) | Women (n = 597) | Both sexes (n = 1563) | Univariate HR (95% CI) | p Value | Multivariate HR (95% CI)* | p Value |
Sex (female) | NA | NA | NA | 1.45 (1.25 to 1.68) | <0.0001 | 1.02 (0.87 to 1.20) | 0.81 |
Age (5 years) | 66.9 (11.8) | 73.2 (11.0) | 69.3 (11.9) | 1.40 (1.34 to 1.45) | <0.0001 | 1.40 (1.34 to 1.46) | <0.0001 |
Current smoker | 341 (35.5) | 139 (23.5) | 480 (30.9) | 0.49 (0.40 to 0.58) | <0.0001 | 1.00 (0.82 to 1.22) | 0.99 |
Co-morbidity† | 187 (19.4) | 133 (22.3) | 320 (20.5) | 1.32 (1.11 to 1.57) | 0.0017 | 1.04 (0.87 to 1.25) | 0.66 |
Previous angina | 258 (26.8) | 157 (26.3) | 415 (26.6) | 1.71 (1.46 to 2.00) | <0.0001 | 1.39 (1.18 to 1.64) | <0.0001 |
Previous coronary revascularisation | 35 (3.6) | 8 (1.3) | 43 (2.8) | 1.01 (0.64 to 1.59) | 0.98 | 1.55 (0.96 to 2.51) | 0.073 |
Peripheral vascular disease | 54 (5.6) | 25 (4.2) | 79 (5.1) | 1.39 (1.02 to 1.88) | 0.036 | 1.13 (0.82 to 1.55) | 0.46 |
Diabetes | 109 (11.4) | 75 (12.7) | 184 (11.9) | 1.78 (1.45 to 2.18) | <0.0001 | 1.70 (1.38 to 2.10) | <0.0001 |
Hypertension | 227 (23.6) | 190 (32.1) | 417 (26.8) | 1.32 (1.12 to 1.55) | 0.0009 | 1.21 (1.02 to 1.42) | 0.028 |
Social deprivation‡ | 363 (37.6) | 222 (37.2) | 585 (37.5) | 0.84 (0.72 to 0.98) | 0.024 | 0.87 (0.74 to 1.02) | 0.088 |
Data are mean (SD) for age, number (%) of patients for other categorical factors, and hazard ratio (HR) with 95% confidence interval (CI) and associated p value from univariate/multivariate Cox models for time to death. The prevalence of each covariate was determined at the time of myocardial infarction.
*Data were missing for 25 (1.6%) patients in the multivariate model.
†Arthritis and chronic obstructive airways disease.
‡Carstairs deprivation category ⩾4.