Table 1.
ST elevation MI | Non-ST elevation MI/unstable angina | ||||||
Treatment | BCS | ESC* | NSF† | Treatment | BCS‡ | ESC§ | NSF† |
Initial | Aspirin, thrombolysis/ PCI | Aspirin, thrombolysis/PCI | Aspirin, thrombolysis | For low risk | Aspirin, LMWH, nitrates, β blockers | Aspirin, LMWH, nitrates, β blockers, clopidogrel | Aspirin, unfractionated heparin or LMWH, β blocker, nitrates |
Subsequent | β Blocker | β Blocker, ACEI <24 hours | β Blocker, ACEI | For high risk | GP IIb/IIIa, angiogram (also intermediate risk) | GP IIb/IIIa, angiogram | Angiogram |
On discharge | Aspirin, β blocker, statin | Aspirin (clopidogrel if aspirin contraindicated), β blocker, statin | Aspirin, β blocker, statin | On discharge | Aspirin, β blocker, statin | Aspirin, clopidogrel (for at least 9 months), β blocker, statin | Aspirin, β blocker, statin |
*Published 2003; †published 2000; ‡published 2001; §published 2002.
ACEI, angiotensin converting enzyme inhibitor; BCS, British Cardiac Society; ESC, European Society of Cardiology; GP, glycoprotein; LMWH, low molecular weight heparin; MI, myocardial infarction; NSF, National Service Framework; PCI, percutaneous coronary intervention.