Table 2.
Variable | LVEF | p Value | |
<50% (n = 754) | ⩾50% (n = 498) | ||
Age (years) | 67.4 (12.2) | 72.3 (10.2) | <0.0001 |
Sex | |||
Men | 522 (69.2%) | 245 (49.2%) | <0.0001 |
Women | 232 (30.8%) | 253 (50.8%) | |
Time in hospital (days) | 15.0 (12.0) | 13.6 (12.3) | 0.047 |
Risk factors | |||
Arterial hypertension | 389 (51.6%) | 304 (61.0%) | <0.001 |
Hyperlipaemia | 256 (34.0%) | 163 (32.7%) | 0.66 |
Diabetes mellitus | 210 (27.9%) | 125 (25.1%) | 0.250 |
Smoking | 269 (35.7%) | 121 (24.3%) | <0.0001 |
Underlying cardiopathy | <0.0001 | ||
Ischaemic cardiopathy | 409 (54.2%) | 207 (41.6%) | |
Valve disease | 95 (12.6%) | 165 (33.1%) | |
Dilated cardiomyopathy | 116 (15.4%) | 0 | |
Other | 134 (17.8%) | 126 (25.3%) | |
Clinical signs | |||
NYHA class IV | 332 (44.0%) | 190 (38.2%) | 0.017 |
Jugular vein congestion | 362 (48.0%) | 200 (40.2%) | 0.030 |
Third heart sound | 149 (19.8%) | 16 (3.2%) | <0.0001 |
Radiographic signs | |||
Cardiomegaly | 613 (81.3%) | 381 (76.5%) | 0.005 |
Alveolar oedema | 118 (15.6%) | 34 (6.8%) | <0.0001 |
ECG signs | |||
Sinus rhythm | 445 (59.0%) | 230 (46.2%) | <0.0001 |
Atrial fibrillation | 232 (30.8%) | 192 (38.6%) | 0.0049 |
Pathological Q wave | 191 (25.3%) | 69 (13.9%) | <0.0001 |
LBBB | 159 (21.1%) | 37 (7.4%) | <0.0001 |
Drug treatment | |||
Digoxin | 271 (36.0%) | 115 (23.1%) | <0.0001 |
Diuretics | 618 (82.0%) | 330 (66.3) | <0.0001 |
ACE inhibitors | 534 (70.8) | 251 (50.4%) | <0.0001 |
ARB | 40 (5.3%) | 25 (5.0%) | 0.842 |
Spironolactone | 121 (16.0%) | 41 (8.2%) | 0.0007 |
Nitrates | 361 (47.9%) | 184 (36.9%) | 0.0004 |
Hydralazine | 43 (5.7%) | 16 (3.2%) | 0.056 |
Vasodilators | 50 (6.6%) | 29 (5.8%) | 0.624 |
Calcium antagonists | 82 (10.9%) | 155 (31.1%) | <0.0001 |
β Blockers | 233 (30.9%) | 118 (23.7%) | 0.011 |
Amiodarone | 130 (17.3%) | 69 (13.9%) | 0.131 |
Antiplatelet agents | 452 (60%) | 258 (51.8%) | 0.007 |
Anticoagulants | 195 (25.9%) | 141 (28.3%) | 0.441 |
Data are mean (SD) or number (%).