Table 6.

 Antibiotic prophylaxis for IE during urological and digestive procedures: Administration of antibiotics respecting contraindications and usual conditions of use and surveillance

	Antibiotic	Dosage and route of administration
		Before (in the hour before the procedure)	After (6 h hours later)
No allergy to β lactams	Amoxicillin then	2 g iv (infusion 30 min)	1 g orally
	gentamicin	1.5 mg/kg iv (infusion 30 min) or im	No second dose
Allergy to β lactams	Vancomycin or	1 g iv (infusion ⩾60 min)	No second dose
	teicoplanin then	400 mg iv (bolus)
	gentamicin	1.5 mg/kg iv (infusion 30 min) or im

Paediatric dosage: amoxicillin 50 mg/kg iv before, 25 mg/kg orally 6 hours later; gentamicin 2 mg/kg (maximum 80 mg); vancomycin 20 mg/kg (maximum 1 g); teicoplanin: no official approval for antibiotic prophylaxis in children.

im, intramuscularly.

If antibiotic prophylaxis concerns a procedure for which the microorganism is a staphylococcus, pristinamycin should be used unless contraindicated.