Table 6.
Multivariate age adjusted odds ratios (with 95% CI) for risk factors and prior disease associated with ST elevation among men and women in the Euro heart survey of ACS
| All | Men | Women | |
| Model I | |||
| BMI (kg/m2) | |||
| Not recorded | 0.62 (0.54 to 0.71) | 0.71 (0.59 to 0.84) | 0.48 (0.38 to 0.60) |
| Overweight (25–30) | 0.92 (0.83 to 1.02) | 0.98 (0.87 to 1.11) | 0.83 (0.69 to 1.00) |
| Obese (>30) | 0.84 (0.75 to 0.96) | 0.90 (0.77 to 1.05) | 0.75 (0.61 to 0.93) |
| Missing data for smoking | 1.52 (1.32 to 1.76) | 1.46 (1.22 to 1.75) | 1.66 (1.29 to 2.13) |
| Current smoker | 1.53 (1.38 to 1.69) | 1.34 (1.20 to 1.50) | 2.31 (1.87 to 2.85) |
| Prior diseases and medication before admission | |||
| MI | 0.82 (0.74 to 0.91) | 0.78 (0.69 to 0.89) | 0.93 (0.77 to 1.12) |
| Chronic angina | 0.60 (0.55 to 0.66) | 0.64 (0.57 to 0.72) | 0.55 (0.47 to 0.65) |
| Revascularisation | 0.56 (0.49 to 0.64) | 0.52 (0.44 to 0.60) | 0.72 (0.55 to 0.93) |
| ASA | 0.66 (0.59 to 0.73) | 0.67 (0.60 to 0.76) | 0.63 (0.53 to 0.74) |
| β Blocker | 0.83 (0.75 to 0.92) | 0.86 (0.76 to 0.97) | 0.77 (0.64 to 0.91) |
| Model II | |||
| BMI (kg/m2) | |||
| Not recorded | 0.62 (0.54 to 0.71) | 0.71 (0.60 to 0.85) | 0.47 (0.37 to 0.59) |
| Overweight (25–30) | 0.94 (0.85 to 1.04) | 1.01 (0.89 to 1.14) | 0.84 (0.69 to 1.01) |
| Obese (>30) | 0.88 (0.78 to 1.00) | 0.96 (0.82 to 1.12) | 0.77 (0.62 to 0.96) |
| Diabetes mellitus | 1.10 (1.00 to 1.22) | 0.97 (0.86 to 1.10) | 1.38 (1.16 to 1.62) |
| Hypertension | 0.75 (0.69 to 0.82) | 0.77 (0.70 to 0.86) | 0.70 (0.60 to 0.83) |
| Smoking not recorded | 1.50 (1.29 to 1.73) | 1.44 (1.21 to 1.73) | 1.63 (1.27 to 2.10) |
| Current smoker | 1.50 (1.35 to 1.65) | 1.31 (1.17 to 1.47) | 2.27 (1.83 to 2.80) |
| Prior diseases and medication before admission | |||
| MI | 0.82 (0.74 to 0.91) | 0.79 (0.70 to 0.89) | 0.90 (0.75 to 1.09) |
| Chronic angina | 0.61 (0.56 to 0.67) | 0.65 (0.58 to 0.73) | 0.56 (0.47 to 0.66) |
| Revascularisation | 0.56 (0.49 to 0.64) | 0.52 (0.44 to 0.60) | 0.70 (0.54 to 0.92) |
| ASA | 0.65 (0.59 to 0.72) | 0.67 (0.59 to 0.76) | 0.62 (0.52 to 0.74) |
| β Blocker | 0.86 (0.78 to 0.95) | 0.88 (0.78 to 1.00) | 0.80 (0.67 to 0.95) |
In model I the effect of increasing BMI is assessed without intermediary variables (diabetes and hypertension). In model II these variables are added. If BMI was analysed as a continuous variable in model I, among the 8855 patients with recorded weight and height, risk of ST elevation was significantly reduced with increasing BMI overall (p = 0.0001; p = 0.0505 among men, p = 0.0008 among women). Corresponding p values for model II were p = 0.0018 overall, among men p = 0.27, among women p = 0.001.