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. 2005 Oct;91(10):1265–1270. doi: 10.1136/hrt.2004.048314

Table 3.

 Randomised controlled trials of nocturnal respiratory support in patients with OSAHS associated with CHF

Trial Patient characteristics Intervention Duration of treatment No of patients Cardiovascular outcomes
CHF cause NYHA class Baseline LVEF (%)
Kaneko et al55 ICM, DCM 2.3 25.0 CPAP 1 month 24 8.8% increase in LVEF, reduced LVESD, reduced heart rate and SBP
Mansfield et al56 Not stated 2.2 37.3 CPAP 3 months 55 5% increase in LVEF, reduced fatigue and overnight urinary noradrenaline excretion, increased disease mastery and emotional wellbeing (CHFQ)

CHFQ, Guyatt chronic heart failure questionnaire; CPAP, continuous positive airway pressure; DCM, dilated cardiomyopathy; ICM, ischaemic cardiomyopathy; LVEF, left ventricular ejection fraction; LVESD, left ventricular end systolic dimension; NYHA, New York Heart Association; SBP, systolic blood pressure.