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Number of patients needed to treat (NNT) over five years to prevent one CHD event (fatal or non-fatal myocardial infarction) in secondary prevention trials
| Cholesterol (mean) | (mmol/l) | Trial data | NNT |
| “High” | 6.8 (range 5.5–8) | 4S (statin) | 22 |
| “Average-high” | 5.9 (above 3.5) | HPS (statin) | 32 |
| “Average-high” | 5.6 (range 4.0–7.0) | LIPID (statin) | 28 |
| “Average” | 5.4 (below 6.2) | CARE (statin) | 33 |
| “Low” | 4.5 | VA-HIT (fibrate) | 23 |
