Table 4.
Results of the simulation study for the 144 combinations of reader-sample size, case-sample size, AUC, and variance components.
| Significance levels |
||||||||
|---|---|---|---|---|---|---|---|---|
| Estimation method | ddf method | N | Mean | Min | Max | Range | SD | CI width mean |
| MLE-jackknife | O | 144 | 0.018 | 0.000 | 0.041 | 0.041 | 0.0144 | 0.231 |
| H | 144 | 0.051 | 0.025 | 0.077 | 0.052 | 0.0105 | 0.173 | |
| D | 144 | 0.043 | 0.017 | 0.067 | 0.050 | 0.0109 | 2.36E+121 | |
| Trapezoid-Delong | O | 144 | 0.019 | 0.000 | 0.047 | 0.047 | 0.0124 | 0.245 |
| H | 144 | 0.054 | 0.032 | 0.082 | 0.051 | 0.0100 | 0.184 | |
| D | 144 | 0.047 | 0.023 | 0.080 | 0.058 | 0.0105 | 2.74E+121 | |
Notes: Min: minimum; Max: maximum; SD: standard deviation; CI width: width of a 95% confidence interval for the difference of the AUC estimates; MLE-jackknife: binormal maximum likelihood AUC estimation and jackknife covariance estimation; Trapezoid-DeLong: trapezoid AUC estimation and DeLong covariance estimation.