Table 3.
Percent identity* | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Drosophila† | Human† | |||||||||
Dm PKA-C1 | Dm PKA-C2 | Dm PKA-C3 | PRKCα | PRKACβ | PRKACγ | PRKX | PRKY | ENSG00000177648 | ||
position‡ | X16969 | X16960 | X16961 | NM_002730 | NM_002731 | NM_002732 | P51817 | O43930 | ||
N-term | ||||||||||
Am PKA-C1 | 1–41 | 82.9 | 20 | 14.6 | 51.3 | 46.2 | 41 | 9.8 | 14.6 | ? |
Am PKA-C2 | 1–36 | 19.4 | 22.2 | 8.3 | 13.9 | 16.7 | 19.4 | 5.6 | 8.3 | ? |
Am PKA-C3 | 1–19 | 15.8 | 10.5 | 31.6 | 21.1 | 21.1 | 21.1 | 21.1 | 15.8 | ? |
small Lobe | ||||||||||
Am PKA-C1 | 42–127 | 93 | 44.2 | 48.8 | 82.6 | 81.4 | 75.6 | 43 | 39.5 | 29.1 |
Am PKA-C2 | 37–122 | 62.8 | 43 | 41.9 | 61.6 | 65.1 | 53.5 | 38.4 | 34.9 | 25.6 |
Am PKA-C3 | 20–103 | 45.2 | 33.3 | 52.4 | 46.4 | 44 | 40.5 | 50 | 47.6 | 22.6 |
large Lobe | ||||||||||
Am PKA-C1 | 128–302 | 97.7 | 52 | 62.9 | 90.9 | 90.3 | 82.9 | 60 | 57.8 | 56.5 |
Am PKA-C2 | 123–297 | 68.6 | 52 | 58.3 | 68 | 68 | 64 | 53.1 | 52.4 | 47.2 |
Am PKA-C3 | 104–278 | 65.1 | 44.6 | 82.9 | 64 | 64 | 62.9 | 76 | 72.1 | 71.4 |
C-term | ||||||||||
Am PKA-C1 | 303–353 | 92.2 | 9.8 | 29.4 | 76.5 | 76.5 | 76.5 | 35.3 | – | 35.3 |
Am PKA-C2 | 298–348 | 45.1 | 5.9 | 29.4 | 43.1 | 43.1 | 43.1 | 25.5 | – | 25.5 |
Am PKA-C3 | 279–331 | 31.4 | 7.5 | 41.5 | 31.4 | 29.4 | 25.5 | 47.2 | – | 45.3 |
The percentage of identical amino acids between the honeybee, the Drosophila and the human subunits with the highest similarity index indicated in bold.
The Drosophila and human subunits and their GenBank/EMBL accession numbers.
Location in amino acids of the different honeybee domains within the protein.