Table 1.
Asthma | ||||||
Control | As2O3 | |||||
4 hrs | 1 hr | 4 hrs | 12 hrs | 24 hrs | 4 hrs | |
EOS | 0.56 ± 0.22 | 5.08 ± 1.37* | 11.12 ± 1.93* | 20.25 ± 2.99* | 48.72 ± 5.38* | 4.69 ± 1.21*† |
NF-κB | 51.47 ± 4.53 | 162.31 ± 9.46* | 255.74 ± 11.10* | 127.59 ± 8.72* | 80.97 ± 6.15# | 75.80 ± 9.33*† |
IκBα | 0.80 ± 0.25 | 0.45 ± 0.04* | 0.23 ± 0.10* | 0.36 ± 0.03* | 0.54 ± 0.07# | 1.56 ± 0.34*† |
Data represent the mean ± SEM of four independent experiments (n = 6 per group). # p < 0.05, * p < 0.01, vs the control mice; † p < 0.01, vs the OVA-challenged mice at 4 hrs.