Table 1.

Effect of Notch-1 and Jagged-1 Silencing on Proliferation of Hepatocytes In Vivo

Treatment	Days Post-Phx	Mean of BrdU Positive Nuclei	Standard Error
Normal liver	2	35.40	5.4
Scra-siRNA	2	40.70	3.6
J1-siRNA	2	7.30*	3.8
N1-siRNA	2	24.70†	3.6
Normal liver	3	59.60	7.6
Scra-siRNA	3	43.00	4.3
J1-siRNA	3	25.90†	3.9
N1-siRNA	3	29.95‡	2.2
Normal liver	4	68.50	3.2
Scra-siRNA	4	63.15	4.2
J1-siRNA	4	29.9*	2.4
N1-siRNA	4	35.4*	4.2

Effect of notch and jagged silencing RNA on hepatocyte proliferation after partial hepatectomy.

P-value of significance against Scra-siRNA treatment.

^*P < .0005;

^†P < .005;

^‡P < .05.