Table 1.
List of patients with oral squamous cell carcinoma in Okinawa, histological differentiation, and detection of Epstein-Barr virus (EBV)
| Patient | Age (years) and sex | Location of the tumour | Stage and differentiation | EBV type | NISH | LMP | EBNA | 30 bp | ||
| 1 | 42 | M | O | IV | W | − | − | − | − | |
| 2 | 42 | M | M | I | W | − | − | − | − | |
| 3 | 48 | M | M | III | W | A+B | + | + | + | + |
| 4 | 70 | M | M | IV | W | A+B | + | + | + | + |
| 5 | 58 | M | F | III | W | A+B | + | + | + | − |
| 6 | 69 | M | T | IV | W | A+B | + | + | + | + |
| 7 | 57 | M | T | I | W | A | + | + | + | + |
| 8 | 67 | M | O | IV | W | A | + | + | + | + |
| 9 | 60 | M | T | IV | W | − | − | − | − | |
| 10 | 59 | M | M | I | W | − | − | − | − | |
| 11 | 77 | M | O | III | W | A | + | + | + | + |
| 12 | 43 | M | T | III | W | A | + | + | + | − |
| 13 | 75 | M | T | IV | W | A | + | + | + | + |
| 14 | 66 | M | F | II | W | A | + | + | + | + |
| 15 | 53 | M | B | I | W | A | + | + | + | + |
| 16 | 80 | F | T | I | W | A | + | + | + | + |
| 17 | 39 | M | L | II | W | − | − | − | − | |
| 18 | 70 | M | T | II | W | A | + | + | + | + |
| 19 | 47 | F | T | II | W | A | + | + | + | + |
| 20 | 60 | M | T | III | W | A | + | + | + | + |
| 21 | 78 | F | M | III | W | A+B | + | + | + | + |
| 22 | 70 | M | T | I | W | B | + | + | + | − |
| 23 | 57 | M | T | II | W | − | − | − | − | |
| 24 | 79 | M | T | II | W | A | + | + | + | + |
| 25 | 78 | M | T | III | W | − | − | − | − | |
| 26 | 65 | M | O | III | W | A | + | + | + | + |
| 27 | 80 | M | F | II | W | B | + | + | + | − |
| 28 | 64 | M | T | III | W | A | + | + | + | + |
| 29 | 86 | M | M | IV | M | A | + | + | + | + |
| 30 | 70 | M | T | O | M | A | + | + | + | + |
| 31 | 69 | M | T | I | M | − | − | − | − | |
| 32 | 55 | M | B | I | M | A | + | + | + | + |
| 33 | 60 | M | L | IV | M | A | + | + | + | + |
| 34 | 71 | M | B | II | M | A | + | + | + | + |
| 35 | 59 | M | T | II | M | A | + | + | + | + |
| 36 | 50 | M | T | II | M | A | + | + | + | + |
| 37 | 39 | M | B | I | M | − | − | − | − | |
| 38 | 70 | M | T | I | M | − | − | − | − | |
| 39 | 78 | M | T | IV | M | − | − | − | − | |
| 40 | 73 | M | F | III | M | A | + | + | + | + |
| 41 | 60 | M | O | II | M | B | + | + | + | − |
| 42 | 80 | M | O | I | M | B | + | + | + | − |
| 43 | 68 | M | L | II | M | B | + | + | + | − |
| 44 | 65 | M | F | III | M | A+B | + | + | + | + |
| 45 | 60 | M | O | III | M | A+B | + | + | + | + |
| 46 | 77 | M | F | IV | M | A+B | + | + | + | + |
| 47 | 47 | F | B | II | M | − | − | − | − | |
| 48 | 67 | M | F | III | M | B | + | + | + | − |
| 49 | 67 | M | O | IV | M | − | − | − | − | |
| 50 | 48 | M | L | II | M | − | − | − | − | |
| 51 | 80 | M | F | III | P | A | + | + | + | + |
| 52 | 57 | M | O | III | P | A | + | + | + | + |
| 53 | 63 | M | O | II | P | A | + | + | + | + |
| 54 | 61 | M | L | IV | P | − | − | − | − | |
Location: B, buccal mucosa; F, mouth floor; L, lower gum; M, maxilla; O, oropharynx; T, tongue.
Differentiation, degree of the histological differentiation of the tumour: M, moderately differentiated; P, poorly differentiated; W, well differentiated. NISH, non-isotopic in situ hybridisation of EBV encoded RNA 1; LMP, immunohistochemical demonstration of latent membrane protein 1 antigen; EBNA, immunohistochemical demonstration of the EBV nuclear antigen 2; 30 bp, 30 bp deletion of LMP-1.