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. 1999 Aug 3;96(16):8855–8860. doi: 10.1073/pnas.96.16.8855

Figure 4.

Figure 4

Redirection of infection of hematopoietic cell lines with biotinylated AdLuc linked to antibodies. (A) The c-Kit+, CD34+, CD44+ cell line M-O7e was infected with 100 μl (moi = 165) of bio-AdLuc linked to avidin (control), 250 ng/ml bio-SCF (SCF-targeted), 20 μg/ml bio-anti-CD117 (antibody to c-Kit, CD117-targeted), 20 μg/ml bio-anti-CD34 (CD34-targeted), or 2.5 μg/ml bio-anti-CD44 antibodies (CD44-targeted). The c-Kit−, CD34+, CD44+ KG-1a cells (B) and c-Kit−, CD34−, CD44+ HL-60 cells (C) were treated identical to M-O7e cells. Luciferase activity at 24 hr after infection is reported as the mean ± SE of duplicate determinations and is representative of two experiments.