Table 2.

Incidence of clonal gene rearrangements in T and B cell lymphomas and leukaemias

	T cell receptor			Immunoglobulin
Disease	TCRB	TCRG	TCRD	IgH	IgK	IgL
Lymphoblastic T cell malignancies
CD3− T ALL	84	85	76	16	0	0
CD3+ T ALL	96	100	58	6	0	0
Lymphoblastic T NHL	79	100		10	33	0
Mature T cell malignancies
T CLL	84	97		3	0	0
T PLL	100	>90	25	7
ATLL	100	100	0	3	0	0
Peripheral T NHL	80	80	20	4	12	0
CTLL/MF	100	100		7	0	0
Lymphoblastic B cell malignancies
Null ALL	9	22	0	95	13	9
Common ALL	41	66	54	99	32	2
Pre B ALL	23	44	20	100	8	20
B ALL	0	0		100
Mature B cell malignancies
B CLL	7	0	0	100	100	30
HCL	0	0	0	100	100	70
B NHL	6	6		100	100	30
Multiple myeloma	5	0	0	100	100	30

Table  adapted from van Dongen and Wolvers-Tettero⁷⁷ and Gill and Gulley⁹⁵.

ALL, acute lymphoblastic leukaemia; ATLL, HTLV1 positive adult T cell leukaemia/lymphoma; CLL, chronic lymphocytic leukaemia; CTLL, cutaneous T cell lymphoma; HCL, hairy cell leukaemia; MF, mycosis fungoides; NHL, non-Hodgkin’s lymphoma; PLL, prolymphocytic leukaemia.