Restriction fragments of adenovirus type 8 (Ad8) were electrophoresed on a 1.2% agarose gel with a HindIII digest of λ DNA (lane m) as molecular weight standard. Lanes A, B, E, and I contain genome types Ad8A (isolates from 1983), Ad8B (from 1984), Ad8E (from 1994), and Ad8I (from 1995), respectively. Ad8 digested with (A) SalI and PstI; (B) SmaI and BamHI; (C) HindIII and SacI.