Table 3.

Immunohistochemical and significant clinicopathological variables of breast cancer related and recurrence free survival in univariate survival analysis

	Surviving breast cancer at 5 years			Recurrence free at 5 years
Variable	n	%	p Value	n	%	p Value
Stage			<0.001			<0.001
I	163	92		163	87
II	212	86		212	77
III	38	54		38	54
Lymph node status			<0.001			<0.001
Negative	247	92		247	86
Positive	166	77		166	68
Histological grade			0.043			0.071
I	108	92		108	85
II	192	85		192	78
III	120	81		120	74
ER status			<0.001			0.124
Positive	323	89		323	80
Negative	95	72		95	74
PR status			0.001			0.183
Positive	261	89		261	80
Negative	157	78		157	76
Nuclear p21WAF1			0.398			0.388
Low <5%	260	84		260	78
High ≥5%	160	87		160	80
Nuclear p53			0.837			0.678
Low <10%	225	86		225	79
High ≥10%	193	84		193	78
Combined p21/p53			0.461			0.782
p21+/p53+	84	84		84	80
p21+/p53−	76	91		76	79
p21−/p53+	109	85		109	76
p21−/p53−	149	83		149	79
Cell proliferation			<0.001			<0.001
Low <20%	230	93		230	89
High ≥20%	184	75		184	64

ER, oestrogen receptor; PR, progesterone receptor.