Table 1.

Haematological data of patients and results of the human androgen receptor gene assay (HUMARA) clonality studies

Patient	Diagnosis	Age	BCR/ ABL	Hb	WBC	Differential blood count	Plt	N-clon	L-clon
1	CNL	52	Absent	140	30.0	Seg 70, Bn 3, My 9, Bas 1, Eo 2, Ly 10, Mo 5	182	M	M
2	CNL	81	Absent	108	35.0	Seg 90, Bn 0, My 0, Bas 0, Eo 0, Ly 9, Mo 1	189	M	P
3	CNL	37	Absent	143	36.2	Seg 64, Bn 15, My 13, Bas 0, Eo 0, Ly 7, Mo 1	273	M	M
4	CNL	72	Absent	89	38.0	Seg 41, Bn 13, My 37, Bas 0, Eo 0, Ly 6, Mo 3	47	M	M
5	CNL	63	Absent	123	24.6	Seg 60, Bn 6, My 17, Bas 5, Ery 2, Ly 9, Mo 1	210	M	M
6	CML	60	b2a2	98	83.5	Seg 28, Bn 14, My 39, Bas 1, Eo 1, Ly 10, Mo 7	718	M	P
7	CML	53	b3a2	101	46.1	Seg 63, Bn 4, My 12, Bas 0, Eo 1, Ly 13, Mo 7	365	M	P
8	CML	41	b3a2	98	239.0	Seg 45, Bn 5, My 39, Bas 3, Eo 0, Ly 2, Mo 6	619	M	P
9	aCML	48	Absent	142	32.7	Seg 27, Bn 4, My 46, Bas 3, Eo 1, Ly 15, Mo 4	460	M	P
10	CML	64	b2a2	116	39.2	Seg 80, Bn 7, My 0, Bas 0, Eo 1, Ly 7, Mo 5	486	M	P
11	CML	58	b3a2	136	24.1	Seg 63, Bn 7, My 0, Bas 2, Eo 0, Ly 22, Mo 6	439	M	M
12	CML	65	b3a2	130	33.9	Seg 59, Bn 4, My 22, Ery 4, Bas 5, Eo 2, Ly 6, Mo 1	246	M	P
13	CMML	83	Absent	100	37.2	Seg 63, Bn 0, My 0, Bas 0, Eo 0, Ly 9, Mo 28	191	M	P
14	CMML	74	Absent	114	8.2	Seg 20, Bn 6, My 0, Bas 0, Eo 0, Ly 51, Mo 23	95	M	P
15	PCV	61	Absent	91	15.4	Seg 80, Bn 4, Ery 4, Bas 0, Eo 0, Ly 10, Mo 2	44	M	ND
16	CIMF	73	Absent	105	12.2	Seg 78, Bn 0, My 0, Bas 1, Eo 4, Ly 16, Mo 1	124	M	P
17	CIMF	83	Absent	116	30.4	Seg 38, Bn 4, My 19, Bas 5, Eo 7, Ly 20, Mo 7	403	M	P
18	LR (smoker)	39	Absent	Normal	14.0	Seg 63, Bn 2, My 2, Bas 1, Eo 4, Ly 25, Mo 3	Normal	M	P
19	LR (diabetes)	50	Absent	88	10.4	Seg 61, Bn 0, My 0, Bas 0, Eo 3, Ly 32, Mo 4	348	P	P
20	LR (fever)	63	ND	99	18.1	Seg 87, Bn 1, Eo 2, Ly 8, Mo2	518	P	P
21	LR	67	ND	ND	21.5	ND	ND	P	P
22	LR (diabetes)	93	ND	ND	20.1	ND	ND	M	ND
23	LR (smoker)	37	ND	134	13.6	Seg 69, Bn 1, Ly24, others 6	204	P	P
24	LR (Sharp sy.)	50	ND	90	7.0	Seg 80, Bn 1, Bas 1, Eo 5, Ly 7, Mo 6	307	M	P
25	LR	53	Absent	142	13.8	Seg 56, Bn 2, Ly35, Mo 7	354	NI	NI
26	LR (smoker)	45	Absent	129	12.5	Seg 66, Bn 4, Eo 6, Ly 20, Mo 4	403	P	P
27–52	Blood donors	20–77	ND	ND	Normal	*	ND	See text

Diagnosis: aCML, atypical chronic myeloid leukaemia; CIMF, chronic idiopathic myelofibrosis; CML, chronic myelogenous leukaemia (chronic phase); CMML, chronic myelomonocytic leukaemia; CNL, chronic neutrophilic leukaemia; LR, leukaemoid reaction; PCV, polycythaemia vera; Sharp sy., Sharp syndrome (a mixed connective tissue disease). Age, age at time of diagnosis; BCR/ABL, status of BCR/ABL translocation; Hb, haemoglobin concentration (g/l); WBC, white blood cell count (×10⁹/l); differential blood count: Seg, segmented neutrophils; Bn, bands; My, myelocytes; Bas(ophils), Eo(sinophils), Ly(mphocytes), Mo(nocytes), Ery(throblasts); Plt, platelet count (×10⁹/l); N-clon/L-clon, clonal status of neutrophils and phytohaemagglutinin expanded lymphocytes using HUMARA with the patterns (M) monoclonal and (P) polyclonal; NI, not informative; ND, not determined.