Table 1.

Prostatic needle biopsy diagnosis and clinical relevance in early detection programme (The Rotterdam algorithm²²)

Diagnosis	Consequence
Inadequate material	Repeat sextant biopsies within 1 year
Benign	Rescreening at the regular intervals
Inflammation, either acute or granulomatous	Rescreening at the regular intervals
Isolated high grade PIN, no cancer, no lesion suspect for cancer	Repeat sextant needle biopsies within 6 months
Lesion suspect for cancer, no definite cancer	Additional biopsies from region suspected of carcinoma within 6 weeks
Definite adenocarcinoma	Referal to clinician/treatment
Other malignancy	Referal to clinician/treatment

PIN, prostatic intraepithelial neoplasia.