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Malignant myoepithelioma/myopithelial carcinoma. (A) Malignant myoepithelioma (MM) with intralobular growth; (B) myoepithelial differentiation is confirmed by anti-smooth muscle actin antibody; (C) MM is composed of a solid proliferation of extremely atypical cells; (D) foci of squamous differentiation are occasionally seen (arrow); (E) MM with spindle cell morphology (note the high mitotic activity). (F) Grade III invasive ductal carcinoma with myoepithelial differentiation.
