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Comparison of Hjc amino acid sequence with homologs found in four archaeal strains (A) and E. coli RuvC (B). Pfu, P. furiosus; Pho, P. horikoshii; Mja, M. jannaschii; Afu, A. fulgidus; Mth, M. thermoautotrophicum. Identical and similar amino acid residues are indicated by red and blue letters, respectively. The four residues indicated by green letters in RuvC are known to constitute the catalytic center (42, 8).
