Table 1.
Vimentin (%) | Desmin (%) | SMA (%) | MSA (%) | HCD (%) | CD34 (%) | S-100 (%) | EMA (%) | CK (%) | |
Leiomyosarcoma | 30 (100) | 28 (93) | 30 (100) | 29 (97) | 29 (97) | 0 | 0 | 14 (47) | 0 |
External soft tissue (n=12) | 12 (100) | 10 (83) | 12 (100) | 11 (92) | 11 (92) | 0 | 0 | 4 (33) | 0 |
0 | 0 | 2 | 0 | 1 | 1 | 0 | 0 | 8 | 0 |
1+ | 0 | 3 | 0 | 6 | 8 | 0 | 0 | 4 | 0 |
2+ | 2 | 3 | 1 | 5 | 0 | 0 | 0 | 0 | 0 |
3+ | 10 | 4 | 11 | 0 | 3 | 0 | 0 | 0 | 0 |
Retroperitoneum and abdomen (n=18) | 18 (100) | 18 (100) | 18 (100) | 18 (100) | 18 (100) | 0 | 0 | 10 (56) | 0 |
0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8 | 0 |
1+ | 2 | 1 | 0 | 1 | 1 | 0 | 0 | 5 | 0 |
2+ | 2 | 3 | 0 | 9 | 0 | 0 | 0 | 5 | 0 |
3+ | 14 | 14 | 18 | 8 | 17 | 0 | 0 | 0 | 0 |
CK, cytokeratin; EMA, epithelial membrane antigen; HCD, heavy-caldesmon; MSA, muscle specific actin; SMA, α smooth muscle actin.
Degree of immunoreactivity: 0, negative; 1+, less than 10% positivity; 2+, 10–50% positivity; 3+, more than 50% positivity.