Table 1.
Details of the uncommon forms of B cell lymphoma encountered in our study
| Case | Site | Method | Initial diagnosis | Percentage of cells positive (numbers indicate CD numbers) | Cell block | Biopsy | Final diagnosis | |||||||||||||||
| 2 | 3 | 4 | 5 | 8 | 10 | 19 | 20 | 23 | IgM | FMC77 | 77 | 19+κ | 19+λ | 5+19 | 4+8 | |||||||
| 1 | Para-aortic | I | Large cell lymphoma | 17 | 5 | 6 | 10 | 79 | 91 | 79 | 3 | 2 | 73 | 94 | 86 | 6 | 0 | 1 | Yes | No | BLBCL | |
| 2 | Mesenteric | I | Lymphoma | 1 | 8 | 1 | 1 | 99 | 99 | 99 | 2 | 24 | 99 | 44 | 99 | 10 | 0 | 0 | Yes | No | BL; partially necrotic | |
| 3 | Right neck | M | Lymphoma | 1 | 4 | 3 | 1 | 1 | 96 | 90 | 98 | 3 | 98 | 96 | 42 | 95 | 8 | 8 | 0 | No | Yes | BLBCL |
| 4 | Left axilla | M | ?HL | 30 | 23 | 99 | 6 | 0 | 68 | 71 | 54 | 71 | 28 | 65 | 1 | 67 | 0 | No | Yes | HL and CLL (on biopsy) | ||
| 5 | Left supraclavicular | M | Reactive | Inadequate for flow cytometry | No | Yes | HL (on biopsy histology) | |||||||||||||||
| 6 | Left neck | M | Reactive | Inadequate for flow cytometry | No | Yes | HL (on biopsy histology) | |||||||||||||||
| 7 | Left neck | M | ?Lymphoma | Inadequate for flow cytometry | No | Yes | HL (on biopsy histology) | |||||||||||||||
| 8 | Mediastinum | I | Reactive | 90 | 77 | 87 | 20 | 2 | 11 | 9 | 23 | 9 | 9 | 6 | 5 | 3 | <1 | No | Yes | HL (on biopsy histology) | ||
| 9 | Left neck | M | Reactive | 69 | 31 | 15 | 20 | No | Yes | HL (on biopsy histology) | ||||||||||||
| 10 | Left inguinal | M | ?HL | 90 | 81 | 93 | 14 | 0 | 13 | 13 | 6 | 9 | 7 | 11 | 10 | 8 | 5 | No | Yes | HL (on biopsy histology) | ||
| 11 | Left neck | M | Inadequate cells | Inadequate for flow cytometry | No | Yes | HL (on biopsy histology) | |||||||||||||||
| 12 | Mediastinal | I | ?Lymphoma | 90 | 77 | 20 | 2 | 11 | 9 | 8 | 9 | 9 | 6 | 5 | 3 | 0 | No | Yes | HL (on biopsy histology) | |||
| 13 | Mediastinal | I | ?Lymphoma | Inadequate for flow cytometry | No | Yes | HL (on biopsy histology) | |||||||||||||||
| 14 | Mediastinal | I | ?Lymphoma | Inadequate for flow cytometry | No | Yes | HL (on biopsy histology) | |||||||||||||||
| 15 | Left cervical | M | ?HL | 28 | 51 | 8 | 1 | 49 | 47 | 4 | 48 | 34 | 23 | 4 | 0 | Yes | Yes | HL (on biopsy histology) | ||||
| 16 | Left neck | M | ?HL | Inadequate for flow cytometry | Yes | Yes | HL (on biopsy histology) | |||||||||||||||
| 17 | Left inguinal | M | ?Lymphoma | 95 | 95 | 18 | 92 | 80 | 0 | 1 | 2 | 2 | 12 | 2 | 1 | 1 | 0 | 1 | No | Yes | HL (on biopsy histology) | |
| 18 | Right axilla | M | ?HL | 82 | 96 | 16 | 2 | 4 | 5 | 3 | 0 | 0 | No | No | HL (on cytology only) | |||||||
| 19 | Left neck | M | Reactive | 88 | 88 | 71 | 87 | 18 | 2 | 12 | 16 | 2 | 31 | 12 | 19 | 16 | 2 | 2 | No | Yes | NLPHL (on biopsy histology) | |
| 20 | Mesenteric | I | ?HL | 99 | 91 | 88 | 13 | 0 | 3 | 3 | 3 | 2 | 5 | No | Yes | NLPHL (on biopsy histology) | ||||||
| 21 | Left submental | M | Lymphoma | 6 | 6 | 3 | 99 | 3 | 1 | 93 | 90 | 4 | 93 | 90 | 4 | 93 | 93 | 0 | No | Yes | MCL (on biopsy histology) | |
| 22 | Right neck | M | Lymphoma | 6 | 11 | 2 | 92 | 5 | 2 | 87 | 95 | 5 | 94 | 59 | 89 | 2 | 80 | 0 | No | Yes | MCL (on biopsy histology) | |
| 23 | Right breast | M | Lymphoma | 2 | 5 | 5 | 100 | 6 | 1 | 99 | 99 | 14 | 99 | 99 | 2 | 97 | 99 | Yes | No | MCL (recurrent) | ||
| 24 | Left parotid | M | Lymphoma | 4 | 2 | 100 | 1 | 1 | 97 | 99 | 12 | 98 | 5 | 95 | 97 | 1 | No | Yes | MCL (on biopsy histology) | |||
| 25 | Mediastinal | I | ?Lymphoma | Inadequate for flow cytometry or cell block | No | Yes | MLBCL | |||||||||||||||
| 26 | Mediastinal | I | ?Lymphoma | Inadequate for flow cytometry or cell block | No | Yes | MLBCL | |||||||||||||||
| 27 | Perihepatic mass | I | Lymphoma/carcinoma | 80 | 62 | 78 | 10 | <1 | 7 | 12 | 5 | 5 | <1 | <1 | Yes | Yes | PTCL (on biopsy histology) | |||||
| 28 | Left neck | M | Malignant | 76 | 42 | 78 | 31 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | No | Yes | PTCL (on biopsy histology) | |||
| 29 | Left cervical | M | Lymphoma | 68 | 63 | 49 | 60 | 11 | 0 | 18 | 14 | 14 | 11 | 15 | 11 | 8 | 0 | 0 | No | Yes | PTCL (on biopsy histology) ALK-1+ | |
| 30 | Right neck | M | Malignant | 93 | 43 | 83 | 41 | 0 | 6 | 1 | 6 | No | Yes | PTCL (on biopsy histology) Lennert’s | ||||||||
| 31 | Right neck | M | Lymphoma | 94 | 78 | 89 | 1 | 92 | 0 | 0 | 1 | 1 | 0 | 84 | Yes | No | PTCL (on cell block histology) | |||||
| 32 | Left neck | M | Malignant | 70 | 0 | 16 | 10 | 13 | Yes | No | PTCL (on cell block histology) | |||||||||||
| 33 | Right calf | M | Lymphoma | 98 | 5 | 96 | 95 | 11 | 1 | 15 | 1 | 1 | <1 | <1 | Yes | No | PTCL (on cell block histology) | |||||
| 34 | Left neck | M | Malignant | 68 | 17 | 51 | 60 | 40 | <1 | 7 | 37 | No | Yes | PTCL (on cell block histology) | ||||||||
| 35 | Left inguinal | M | Lymphoma/carcinoma | 70 | 42 | 26 | 3 | 30 | 30 | 5 | 5 | Yes | Yes | PTCL (on cell block histology) | ||||||||
| 36 | Left inguinal | M | Lymphoma | 85 | 61 | 83 | 24 | 1 | 12 | 12 | 9 | <1 | 6 | 6 | <1 | <1 | Yes | No | PTCL (on cell block histology) | |||
| 37 | Left leg | M | Lymphoma | 100 | 7 | 91 | 60 | 6 | 2 | 12 | 10 | 21 | 13 | No | Yes | PTCL (recurrent) | ||||||
| 38 | Right inguinal | M | Lymphoma/carcinoma | 94 | 58 | 86 | 22 | 1 | 14 | 13 | 5 | 17 | 2 | 7 | 5 | 1 | 0 | Yes | Yes | TCRBCL (on biopsy histology) | ||
| 39 | Left neck | M | Probable carcinoma | 98 | 41 | 90 | 48 | 1 | 17 | 12 | Yes | Yes | TCRBCL (on biopsy histology) | |||||||||
| 40 | Left neck | M | ?Lymphoma | 87 | 9 | 6 | 6 | No | Yes | TCRBCL (on biopsy histology) | ||||||||||||
| 41 | Right neck | M | ?Lymphoma | 89 | 75 | 48 | 83 | 26 | 27 | 14 | 11 | 5 | 25 | 17 | 3 | 6 | 2 | 1 | No | Yes | TCRBCL (on biopsy histology) | |
| 42 | Left neck | M | ?Lymphoma | 79 | 55 | 76 | 18 | 6 | 28 | 30 | 6 | 30 | 35 | 26 | 20 | 8 | 0 | No | Yes | TCRBCL (on biopsy histology) | ||
BL, Burkitt lymphoma; BLBCL, Burkitt-like large B cell lymphoma; CLL, chronic lymphocytic leukaemia; FNA, fine needle aspiration; I, image guided FNA; M, manually guided FNA; MCL, mantle cell lymphoma; MLBCL, mediastinal (thymic) large B cell lymphoma; NLPHL, nodular lymphocyte predominant Hodgkin lymphoma; PTCL, peripheral T cell lymphoma; TCRBCL, T cell rich B cell lymphoma.