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. 2004 Feb;57(2):193–195. doi: 10.1136/jcp.2003.12914

Table 1.

Influence of core needle biopsy number and core index on agreement between preoperative and postoperative histopathology

Number of cores Core index
N Median Range p Value Median Range p Value
Type
    Agree 78 3 1–7 0.415 161 15–1260 0.331
    Disagree 35 2 1–5 144 20–760
Grade
    Agree 67 2 1–5 0.172 153 20–812 0.190
    Disagree 46 3 1–7 151 15–1260
Mitoses
    Agree 66 2 1–4 0.300 145.5 20–812 0.148
    Disagree 47 3 1–7 171 15–1260
Tubule formation
    Agree 60 3 1–7 0.738 145.5 15–1260 0.983
    Disagree 53 2 1–5 160 20–812
Pleomorphism
    Agree 64 3 1–7 0.615 152 42–1260 0.530
    Disagree 49 2 1–4 153 15–660

In total, 113 patients were examined to find out whether the number of cores collected during the diagnosis of a suspicious lesion correlated with the likelihood of agreement between preoperative and postoperative histology. This was assessed by two methods: (1) a count of the number of cores and (2) an index of the amount of material examined by the pathologist (as described in Patients and methods). Mitoses, tubule formation, and nuclear pleomorphism were components of tumour grade. The p value was determined by binary logistic regression.