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. 2004 Apr;57(4):394–401. doi: 10.1136/jcp.2002.004978

Figure 1.

Figure 1

Laryngeal preneoplastic and neoplastic conditions stained by antibodies to factor VIII. (A) Vessels in the stroma of unaltered epithelium. (B) Severe epithelial dysplasia with prominent blood vessels. (C) Well differentiated squamous cell carcinoma with vessels in circumferential arrangements. (D–F) Moderately differentiated laryngeal squamous cell carcinoma with vessels extending from the stroma in the direction of the epithelial basement membrane (directional angiogenesis).