Figure 4.

Observed sizes of a 2.1 mm diameter metastasis as measured in the plane of section A as a function of the length of segment pr from fig 3, when the distance between the sections is 2 mm. Situation 1 in fig 3 is shown by the point at the right edge of the graph (0.64 mm lowest apparent size), situation 3 with the maximum size identified is represented at the left edge, and situation 2 at the middle is highlighted by the broken line. With a sectioning distance of 1 mm, the apparent size can vary between 2.1 mm and 1.85 mm (broken line).