Table 1.

Staining for CDX-2 in primary ovarian carcinomas and metastatic carcinomas to the ovary

Lesions	No. of cases	No. of CDX-2 positive cases	CDX-2 immunoreactive tumours (%)
Serous carcinoma (TMA)	129	0	0%
Endometrioid carcinoma (TMA)	68	0	0%
Clear cell carcinoma (TMA)	24	0	0%
Mucinous carcinoma (CS)	16	1*	0%*
Metastatic carcinoma from (CS)
Colon†	15	13‡	93%
Appendix	1	1	100%
Stomach	2	0	0%
Pancreas	1	0	0%
Cervix	1	0	0%

*<25% of tumour cells; †13 moderately and 2 poorly differentiated adenocarcinomas. The ovarian tumours showed a predominant “pseudoendometrioid” pattern in all 13 cases, with areas of mucinous histology in 3 cases. Two ovarian metastases consisted of the same poorly differentiated adenocarcinoma, as in their colonic primaries. ‡The two poorly differentiated adenocarcinomas were negative for CDX-2.

CS, conventional slides; TMA, tissue microarray.