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. 2004 Sep;57(9):973–979. doi: 10.1136/jcp.2003.015875

Figure 1.

Figure 1

 Lamina propria T cell, macrophage, and B/plasma cell counts (mean ±SEM) in colonic biopsies from control patients (group A), patients with Clostridium difficile associated diarrhoea (CDAD) with absent/minimal inflammation (group B), and patients with pseudomembranous colitis (PMC). Biopsies from the PMC group were obtained from (1) mucosa adjacent to pseudomembrane (group C) and (2) mucosa with overlying pseudomembrane and with a “volcano” lesion (group D). Compared with controls (group A), macrophage and B/plasma cell counts (but not T cell counts) were significantly reduced in all groups of biopsies from patients with CDAD (groups B, C, and D). B/plasma cell counts were also significantly lower in group D biopsies, compared with those in groups B (+p < 0.001) and C (#p < 0.01).