Table 1.
Patients | |
Total patients | 126 |
Sex | |
Female | 42 (33%) |
Male | 84 (67%) |
Mean (SD) age at first HP | 63.7 years (10.8) |
No of HPs/patient | |
1 | 109 (87%) |
2 | 14 (11%) |
3 | 2 (1.6%) |
4 | 1 (0.8%) |
Mean (SD) number HP/patient | 1.17 (0.5) |
HP location by patient | |
Left side only | 89 (71%) |
Right side only | 32 (25%) |
Both sides | 4 (3%) |
Unknown | 1 (0.8%) |
Hyperplastic polyps | |
Total number | 147 |
Left colon | 109 (74%) |
Right colon | 37 (25%) |
Unknown site | 1 (0.7%) |
Number with K-ras mutation | 15 of 143 assayed (10%) |
Location of HPs with K-ras mutation | |
Rectum | 5 |
Sigmoid | 10 |
Size of HP | |
15 HPs with K-ras mutation | 3.2 mm |
128 HPs without K-ras mutation | 3.25 mm |
Number with APC LOH | 0 of 133 assayed |
Number with MSI | 0 of 55 assayed |
HP in same segment | |
As an adenoma* | |
Yes | 68 (48%) |
No | 73 (52%) |
*1 patient had HP of unknown location, 4 had carcinoma and no adenoma, 1 had small bowel carcinoma.
APC, adenomatous polyposis coli; HP, hyperplastic polyp; LOH, loss of heterozygosity; MSI, microsatellite instability.