Table 1.
Patient | Perforin | Granzyme B | ||||||
Epi | Fib | Macro | Lymph | Epi | Fib | Macro | Lymph | |
IPF | ||||||||
1 | 1 | 0 | 0 | 2 | 1 | 0 | 0 | 1 |
2 | 1 | 1 | 0 | 3 | 1 | 1 | 1 | 1 |
3 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 |
4 | 1 | 0 | 0 | 3 | 1 | 1 | 0 | 3 |
5 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 |
6 | 1 | 1 | 0 | 2 | 1 | 1 | 0 | 2 |
7 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 2 |
8 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2 |
Controls | ||||||||
1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Grades of IPF: 0, no positive cells; 1, <10% of cells positive; 2, 10–49% of cells positive; 3, >50% of cells positive.
Epi, epithelium; Fib, fibroblast; IPF, idiopathic pulmonary fibrosis; Lymph, lymphocyte; Macro, macrophage.