Table 4.
Comparison of characteristics of patients with Clostridium perfringens and those with non-perfringens clostridium bacteraemia
Characteristics of blood culture isolate | Number of patients (%) | p Value | |
Clostridium perfringens (n = 30) | Other clostridium species (n = 8) | ||
Sex | NS | ||
Male | 18 (60) | 5 (63) | |
Female | 12 (40) | 3 (38) | |
Mean age (SD) | 70 (20.8) | 41 (33.2) | <0.05 |
Underlying diseases* | |||
Gastrointestinal tract disease | 8 (27) | 3 (38) | NS |
Hepatobiliary tract disease | 9 (30) | 2 (25) | NS |
Malignancy | 7 (23) | 4 (50) | NS |
Hypertension | 10 (33) | 1 (13) | NS |
Diabetes mellitus | 6 (20) | 1 (13) | NS |
Cerebrovascular accident | 5 (17) | 1 (13) | NS |
Immobilisation and/or bed sore | 3 (10) | 1 (13) | NS |
Chronic renal failure | 3 (10) | 0 (0) | NS |
Diagnosis | |||
Primary bacteraemia | 8 (27) | 5 (63) | NS |
Cholecystitis/cholangitis | 12 (40) | 0 (0) | <0.05 |
Other intra-abdominal infection | 5 (17) | 2 (25) | NS |
Infected gangrene of extremities | 3 (10) | 0 (0) | NS |
Infected bed sore | 1 (3) | 1 (13) | NS |
Pneumonia | 1 (3) | 0 (0) | NS |
Community/hospital acquired | |||
Community | 27 (90) | 3 (38) | |
Hospital | 3 (10) | 5 (63) | <0.005 |
Number of positive blood cultures | |||
1 | 27 (90) | 7 (88) | NS |
2 | 3 (10) | 1 (13) | |
Mono/polymicrobial bacteraemia | |||
Monomicrobial | 15 (50) | 4 (50) | NS |
Polymicrobial | 15 (50) | 4 (50) | NS |
Mortality | 8 (26) | 3 (38) | NS |
*The percentages add up to more than 100% because some patients had more than one underlying disease.
NS, not significant.