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. 2005 Mar;58(3):281–284. doi: 10.1136/jcp.2003.014290

Figure 1.

Figure 1

 Representative electropherogram showing microsatellite instability (MSI) and loss of heterozygosity (LOH). (A) MSI for marker D3S659. The normal DNA (lane 6) shows a single peak (homozygous, non-informative case), whereas tumour DNA (lane 7) contains a novel peak (122.6 bp). (B) Electropherogram showing LOH for Bat 25: the middle trace (lane 22) shows normal DNA and the lower trace (lane 23) shows tumour DNA with loss of the larger allele. Lane 1 represents the external marker that was run with all samples.