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(A) Bouin’s fixed (BF) prostate biopsy stained for MCM2 showing no reactivity. (B) The corresponding formalin fixed biopsy shows strong immunoreactivity, predominantly in the basal cell compartment. (C) BF prostate biopsy stained for p27 shows weak nuclear staining with abundant cytoplasmic positivity, whereas the formalin fixed biopsy (D) shows strong nuclear positivity with very weak cytoplasmic staining.
