Table 6.
Log rank test | Cox regression test* | |||
p Value | p Value | HR | 95% CI | |
Cyclin A | 0.015 | 0.044 | 0.57 | 0.33 to 0.98 |
Cyclin B1 | 0.557 | |||
Cyclin C | 0.069 | |||
Cyclin D1 | 0.420 | |||
Cyclin D3 | 0.162 | |||
Cyclin E | 0.070 | |||
Cyclin H | –† | |||
CCNA amplification | 0.440 | |||
CCNB1 amplification | 0.623 | |||
CCNC amplification | 0.019 | 0.049 | 1.72 | 1.00 to 2.94 |
CCND1 amplification | 0.280 | |||
CCND3 amplification | 0.971 | |||
CCNE amplification | 0.611 | |||
CCNH amplification | 0.468 | |||
Tumour differentiation | 0.044 | 0.062 | 0.51 | 0.25 to 1.04 |
Dukes stage | <0.001 | <0.001 | 4.89 | 3.39 to 7.10 |
*Including only parameters with significance in the univariate test and adjusted for age; †all tumours were immunopositive for cyclin H.